The ketoconazole cocrystal from slurry technique confirmed an improved solubility by 50 times compared to ketoconazole. This research showed that cocrystallization between ketoconazole and ascorbic acid were successfully fashioned and enhanced the solubility of the drug. New peaks attribute of cocrystal appear at a 2θ value of 16.94° and 24.58° In addition, synthesized cocrystal have unique behavior crystal, melting point and FTIR spectrum in comparison with single element.
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Given this building of the time period ‘specified minimum sentence’ in s 5 of the POA, one is led to the inexorable conclusion that s 5 of the CGHA does certainly prescribe a ‘specified minimum sentence’ of fine.
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